- Naam
- Utrecht Cardiovasculair Cohort – Cardiovasculair Risico Management
- Afkorting
- UCC-CVRM
- Beschrijving
All patients who come for a first-time visit to one of the departments of the Center for Circulatory Health at the UMC Utrecht for the evaluation of a symptomatic vascular disease or an asymptomatic vascular condition, are enrolled. A minimum set of data, according to the Dutch Cardiovascular Risk Management Guidelines, is collected in all patients at all departments. A questionnaire is completed which includes demographic data, medical history, family history of premature
CVD, physical activity, smoking, alcohol consumption, obstetric history and medication use. Measurements taken during the first visit in the hospital include body weight, height, systolic and diastolic blood pressure, serum lipids (total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides), glycated haemoglobin (Hb1Ac), renal function (serum creatinine with eGFR estimated using the Chronic Kidney Disease-Epidemiology (CKD-EPI) formula), and haemoglobin. Spare blood samples (heparin, full blood) are taken and stored at –80_ Celsius.
All data is stored in the electronic health care records (EHR) and in dedicated databases. Linkage of the UCC-CVRM database with EHRs, with regional and national registries is performed. Written informed consent is obtained.
UCC-CVRM enrollment as described above from 2015 up to 2020. In 2021, UCC-CRVM is preparing the enrollment through direct extraction of CVRM information, offering of the cardiovascular questionnaire and the request for informed consent through the hospital portal. This approach will start in full swing in 2022.
- Gebruiksdoel
The Utrecht Cardiovascular Cohort initiative aims to create an infrastructure for uniform registration of cardiovascular information in routine clinical practice for patients referred for cardiovascular care at the University Medical Center Utrecht, the Netherlands. This infrastructure will promote optimal care according to guidelines, continuous quality control in a learning healthcare system and creation of a research database.
- Operationeel
- Ja
- Contactgegevens publiek
UMC Utrecht
Prof.Dr. Michel L. Bots, chairman of the UCC steering committee
088 755 9352
M.L.Bots@umcutrecht.nl
Julius Center for Health Sciences and Primary Care, Heidelberglaan 100
3584 CX Utrecht
www.umcutrecht.nl/ucc
- Beheerder gegevensbron
- Universitair Medisch Centrum Utrecht (UMCU)
- Eigenaar gegevensbron
- Universitair Medisch Centrum Utrecht (UMCU)
- Actualisatiedatum
- 04-10-2021
- Wettelijke verplichting
- Nee
- Type verplichting
- Vrijwillig
- Welke wetten
Broad informed consent is obtained in UCC-CVRM for storage of blood samples, follow-up procedures, and for contacting participants in the future.
- Opdrachtgever(s)
- Universitair Medisch Centrum Utrecht (UMCU)
- Belangrijkste financier(s)
- Universitair Medisch Centrum Utrecht (UMCU)
- Financier is overheid
- Ja
- Financiering gegevensbron
UMC Utrecht
Grants have been and will be obtained for in-depth measurements in all or smaller groups of participants typically for dedicated project. An example is a ZonMw GGG grant (#848034001)
- Type gegevensverzameling
-
- Longitudinale studie
- Biobank
- Databank of dataset
- Electronic health care records
- Kwaliteitsregister
- Patiëntenregistratie
- Real world data
- Registratie
- Gekoppelde categorieën
-
- Biologische factoren
- Gezondheidsgedrag of leefstijl
- Preventie gericht op verschillende invalshoeken
- Ziekenhuiszorg
- Ziekten en aandoeningen
- Gekoppelde trefwoorden
-
- Alcohol intake
- Blood pressure
- Cause of death
- CT imaging
- Demographics
- Diabetes
- ECG
- Echocardiography
- Education
- Electronic Health care Records
- Ethnicity
- Family history of cardiovascular disease
- Follow-up
- Hospitalisaton
- Kidney function
- Learning Health Care System
- Lipids
- Medication
- Overweight
- Prescribed medication
- Real Word Data
- Smoking
- Geografische dekking
- Predominantly Utrecht
- Eenheden in de gegevens
As of Januari 1, 2021, present over 8000 participants have been invited for participation in UCC-CVRM.
- Methode van gegevensverzameling
- A questionnaire completed by the patient, that is entered in the electronic health care record of the patient visiting the UMC Utrecht. Information from the electronic health care record of the patient for assessment of blood pressure measurements, anthropometry, laboratory values. From 2022, data is being extracted from the electronic health care records, questionnaire data is offered to be completed on line in the hospital portal, and the informed consent is offered to be completed on line in the hospital portal.
- Type persoon/instelling die de gegevensbron invult
Patiënten: => questionnaire
Specialisten: => clinical information
Verpleegkundigen => clinical information
Anders, nl.=> all information for the UUC-CVRM is extracted from the EH
- Specialisme
-
- Cardiologie
- Suspected cardiovascular condition
- Sector
- Derdelijnszorg
- Eerste meetjaar
- 2015
- Meest recente meetjaar
- 2020
- Operationeel
- Ja
- Frequentie van aanleveren
Dagelijks
- Bijzonderheden
The users so far have been: Medical MSC students, PhD students, Staff members of the departments involved in the UCC-CVRM. Their use has been on addressing scientific research questions and for grant proposals submission.
- Informatie die geregistreerd wordt
Jaar Aantal Steekproefgrootte Responspercentage Dekkingsgraad 2020 One, the UMC Utrecht Of those invited to participate in UCC-CVRM, overall between 50-60% provide an signed informed consent. This percentage varies across the recruiting departments from 40-85%: being geriatric department, vascular medicine, vascular surgery, cardiology, neurology, nephrology, obstetrics, cardiothoracic surgery There is no sample size estimation. We strive to enrol all eligible patients!.
- Beschikbaarheid gegevens
- Ja
- Voorwaarden beschikbaarheid
Investigators from the participating departments of Center for Circulatory Health have free access to the UCC-CVRM database. Researchers can request existing data and samples for analysis of new markers. Tailor made datasets will be distributed to the investigator upon approval of request by the UCC – CVRM Steering Committee. Approval mainly involves checking feasibility, potential overlap with previous requests, material availability, and need for involvement of specific disciplines. After data distribution, automated checks on progress will be made at regular intervals. For investigators outside these departments or from outside the UMC Utrecht, a similar procedure is available. When new variables are measured in stored samples these must be added the UCC database. A copy of the distributed dataset remains at the UMC Utrecht for long term storage. Details on available data, the application form and procedure can be found on our website. For researchers outside participating departments we charge a data access fee per dataset to cover our costs for inclusion, maintenance, quality control and management.
- Beschikbaarheid gegevens online
-
Ja
Utrecht Cardiovasculair Cohort (UCC) - CVRM - UMC Utrecht
Utrecht Cardiovasculair Cohort (UCC) - CVRM // - UMC Utrecht
- Contactgegevens publiek
UMC Utrecht
Prof.Dr. Michel L. Bots, chairman of the UCC steering committee
088 755 9352
M.L.Bots@umcutrecht.nl
Julius Center for Health Sciences and Primary Care, Heidelberglaan 100
3584 CX Utrecht
www.umcutrecht.nl/ucc
- Beschikbare publicaties
- Afnemers/gebruikers
-
- Medical MSC students
- PhD students
- Staff members of the departments involved in the UCC-CVRM.
- Verwachte wijzigingen
UCC-CVRM is an ongoing study without a formal end. As such more information will become available over time in terms of results, patient enrolment, enrichment of the database through linkage within the UMC Utrecht, and with regional and national registries (e.g. medication use follow-up, morbidity, mortality).
UCC-CVRM enrollment as described above from 2015 up to 2020. In 2021, UCC-CRVM is preparing the enrollment through direct extraction of CVRM information, offering of the cardiovascular questionnaire and the request for informed consent through the hospital portal. This approach will start in full swing in 2022.